Current Build

Переводит команда Health Samurai. Приглашаем поучаствовать в русификации стандарта FHIR: GitHub, Email.

Allergyintolerance.profile.json

Patient Care Work GroupMaturity Level: N/ABallot Status: InformativeCompartments: Patient, Practitioner, RelatedPerson

Raw JSON (каноническая форма + also see JSON Format Specification)

StructureDefinition for allergyintolerance

{
  "resourceType" : "StructureDefinition",
  "id" : "AllergyIntolerance",
  "meta" : {
    "lastUpdated" : "2019-05-17T12:34:53.932+00:00"
  },
  "text" : {
    "status" : "generated",
    "div" : "<div>!-- Snipped for Brevity --></div>"
  },
  "extension" : [{
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode" : "trial-use"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger" : 3
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category",
    "valueCode" : "patient"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode" : "pc"
  }],
  "url" : "http://hl7.org/fhir/StructureDefinition/AllergyIntolerance",
  "version" : "3.6.0",
  "name" : "AllergyIntolerance",
  "status" : "draft",
  "date" : "2019-05-17T12:34:53+00:00",
  "publisher" : "Health Level Seven International (Patient Care)",
  "contact" : [{
    "telecom" : [{
      "system" : "url",
      "value" : "http://hl7.org/fhir"
    }]
  },
  {
    "telecom" : [{
      "system" : "url",
      "value" : "http://www.hl7.org/Special/committees/patientcare/index.cfm"
    }]
  }],
  "description" : "Risk of harmful or undesirable, physiological response which is unique to an individual and associated with exposure to a substance.",
  "purpose" : "To record a clinical assessment of a propensity, or potential risk to an individual, of an adverse reaction upon future exposure to the specified substance, or class of substance.",
  "fhirVersion" : "3.6.0",
  "mapping" : [{
    "identity" : "rim",
    "uri" : "http://hl7.org/v3",
    "name" : "RIM Mapping"
  },
  {
    "identity" : "w5",
    "uri" : "http://hl7.org/fhir/fivews",
    "name" : "FiveWs Pattern"
  },
  {
    "identity" : "v2",
    "uri" : "http://hl7.org/v2",
    "name" : "HL7 v2 Mapping"
  }],
  "kind" : "resource",
  "abstract" : false,
  "type" : "AllergyIntolerance",
  "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/DomainResource",
  "derivation" : "specialization",
  "snapshot" : {
    "element" : [{
      "id" : "AllergyIntolerance",
      "path" : "AllergyIntolerance",
      "short" : "Allergy or Intolerance (generally: Risk of adverse reaction to a substance)",
      "definition" : "Risk of harmful or undesirable, physiological response which is unique to an individual and associated with exposure to a substance.",
      "comment" : "Substances include, but are not limited to: a therapeutic substance administered correctly at an appropriate dosage for the individual; food; material derived from plants or animals; or venom from insect stings.",
      "alias" : ["Allergy",
      "Intolerance",
      "Adverse Reaction"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance",
        "min" : 0,
        "max" : "*"
      },
      "constraint" : [{
        "key" : "dom-2",
        "severity" : "error",
        "human" : "Если ресурс встроен в другой ресурс, он НЕ ДОЛЖЕН содержать описательной части",
        "expression" : "contained.contained.empty()",
        "xpath" : "not(parent::f:contained and f:contained)",
        "source" : "DomainResource"
      },
      {
        "key" : "dom-4",
        "severity" : "error",
        "human" : "Если ресурс встроен в другой ресурс, он НЕ ДОЛЖЕН иметь meta.versionId или meta.lastUpdated",
        "expression" : "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
        "xpath" : "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
        "source" : "DomainResource"
      },
      {
        "key" : "dom-3",
        "severity" : "error",
        "human" : "Если ресурс встроен в другой ресурс, где-то в родительском ресурсе на него ДОЛЖНА БЫТЬ дана ссылка or SHALL refer to the containing resource",
        "expression" : "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
        "xpath" : "not(exists(for $contained in f:contained return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
        "source" : "DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
          "valueBoolean" : true
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
          "valueMarkdown" : "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
        }],
        "key" : "dom-6",
        "severity" : "warning",
        "human" : "A resource should have narrative for robust management",
        "expression" : "text.div.exists()",
        "xpath" : "exists(f:text/h:div)",
        "source" : "DomainResource"
      },
      {
        "key" : "dom-5",
        "severity" : "error",
        "human" : "If a resource is contained in another resource, it SHALL NOT have a security label",
        "expression" : "contained.meta.security.empty()",
        "xpath" : "not(exists(f:contained/*/f:meta/f:security))",
        "source" : "DomainResource"
      },
      {
        "key" : "ait-1",
        "severity" : "error",
        "human" : "AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error.",
        "expression" : "verificationStatus='entered-in-error' or clinicalStatus.exists()",
        "xpath" : "f:verificationStatus/@value='entered-in-error' or exists(f:clinicalStatus)"
      },
      {
        "key" : "ait-2",
        "severity" : "error",
        "human" : "AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error",
        "expression" : "verificationStatus!='entered-in-error' or clinicalStatus.empty()",
        "xpath" : "f:verificationStatus/@value!='entered-in-error' or not(exists(f:clinicalStatus))"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Entity. Role, or Act"
      },
      {
        "identity" : "rim",
        "map" : "Observation[classCode=OBS, moodCode=EVN]"
      }]
    },
    {
      "id" : "AllergyIntolerance.id",
      "path" : "AllergyIntolerance.id",
      "short" : "Logical id of this artifact",
      "definition" : "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
      "comment" : "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "id"
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "AllergyIntolerance.meta",
      "path" : "AllergyIntolerance.meta",
      "short" : "Метаданные ресурса",
      "definition" : "Метаданные ресурса. Это такая информация, которая поддерживается инфраструктурой. Изменения этой информации не всегда можно ассоциировать с версионными изменениями ресурса.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.meta",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Meta"
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "AllergyIntolerance.implicitRules",
      "path" : "AllergyIntolerance.implicitRules",
      "short" : "Свод правил, в соответствии с которыми создавалось это содержимое",
      "definition" : "Ссылка на свод правил, которым следовали при создании этого ресурса и которые необходимо понимать при обработке этого содержимого. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
      "comment" : "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.implicitRules",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "uri"
      }],
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
      "isSummary" : true
    },
    {
      "id" : "AllergyIntolerance.language",
      "path" : "AllergyIntolerance.language",
      "short" : "Язык содержимого ресурса",
      "definition" : "Основной язык, на котором написан ресурс.",
      "comment" : "Язык указывается для поддержки предварительной обработки текстов и доступности для понимания (например при преобразовании текста в речь используется языковой тег). HTML-тег language в описательной части применяется к этой описательной части. Языковой тег ресурса может использоваться для указания языков других представлений, генерируемых из данных ресурса\n\nНе все содержание ресурса должно быть на указанном основном языке. Resource.language нельзя автоматически принимать за язык описательной части. Если язык указан, его также следует указать в элементе div в HTML (информацию о связи между xml:lang и HTML-атрибутом lang см. в правилах HTML5).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.language",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
          "valueCanonical" : "http://hl7.org/fhir/ValueSet/all-languages"
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "Language"
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
          "valueBoolean" : true
        }],
        "strength" : "preferred",
        "description" : "Естественный язык.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/languages"
      }
    },
    {
      "id" : "AllergyIntolerance.text",
      "path" : "AllergyIntolerance.text",
      "short" : "Краткое текстовое изложение ресурса для интерпретации человеком",
      "definition" : "Человекочитаемая описательная часть, содержащая краткое изложение ресурса, которая может использоваться для представления содержимого ресурса человеку. От описательной части не требуется кодировать все структурированные данные, но она должна содержать достаточно сведений, чтобы простое её прочтение человеком было \"клинически безопасным\". Определения ресурсов могут описывать, какое содержимое должно быть представлено в описательной части для обеспечения клинической безопасной.",
      "comment" : "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
      "alias" : ["narrative",
      "html",
      "xhtml",
      "display"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "DomainResource.text",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Narrative"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Act.text?"
      }]
    },
    {
      "id" : "AllergyIntolerance.contained",
      "path" : "AllergyIntolerance.contained",
      "short" : "Вложенные, встроенные инлайн ресурсы",
      "definition" : "Эти ресурсы не обладают независимым существованием вне ресурса, который их содержит - их нельзя идентифицировать независимо, и они не могут иметь своей собственной независимой транзакционной области действия.",
      "comment" : "Этого не следует делать, когда содержимое может быть идентифицировано должным образом, поскольку, потеряв идентификацию, будет чрезвычайно сложно (и контекстно-зависимо) снова восстановить её. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
      "alias" : ["inline resources",
      "anonymous resources",
      "contained resources"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.contained",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Resource"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "AllergyIntolerance.extension",
      "path" : "AllergyIntolerance.extension",
      "short" : "Дополнительное содержимое, определенное реализаторами",
      "definition" : "Может использоваться для представления дополнительной информации, не являющейся частью базового определения ресурса. Чтобы сделать использование расширений надежным и управляемым, существует строгий набор управления применительно к определению и использованию расширений. Хотя каждому реализатору разрешается определять расширения, имеется набор требований, которые должны выполняться в рамках определения расширения.",
      "comment" : "Не должно быть никаких предрассудков по использованию расширений любыми приложениями, проектами или стандартами - вне зависимости от учреждения или юрисдикции, которые используют или задают расширение. Именно использование расширений позволяет спецификации FHIR сохранять простоту для всех.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "AllergyIntolerance.modifierExtension",
      "path" : "AllergyIntolerance.modifierExtension",
      "short" : "Расширения, которые нельзя игнорировать",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "Не должно быть никаких предрассудков по использованию расширений любыми приложениями, проектами или стандартами - вне зависимости от учреждения или юрисдикции, которые используют или задают расширение. Именно использование расширений позволяет спецификации FHIR сохранять простоту для всех.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "AllergyIntolerance.identifier",
      "path" : "AllergyIntolerance.identifier",
      "short" : "External ids for this item",
      "definition" : "Business identifiers assigned to this AllergyIntolerance by the performer or other systems which remain constant as the resource is updated and propagates from server to server.",
      "comment" : "This is a business identifier, not a resource identifier (see [discussion](resource.html#identifiers)).  It is best practice for the identifier to only appear on a single resource instance, however business practices may occasionally dictate that multiple resource instances with the same identifier can exist - possibly even with different resource types.  For example, multiple Patient and a Person resource instance might share the same social insurance number.",
      "requirements" : "Allows identification of the AllergyIntolerance as it is known by various participating systems and in a way that remains consistent across servers.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.identifier",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Identifier"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.identifier"
      },
      {
        "identity" : "v2",
        "map" : "IAM-7"
      },
      {
        "identity" : "rim",
        "map" : "id"
      }]
    },
    {
      "id" : "AllergyIntolerance.clinicalStatus",
      "path" : "AllergyIntolerance.clinicalStatus",
      "short" : "active | inactive | resolved",
      "definition" : "The clinical status of the allergy or intolerance.",
      "comment" : "Refer to [discussion](extensibility.html#Special-Case) if clincalStatus is missing data.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.clinicalStatus",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "condition" : ["ait-1",
      "ait-2"],
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the status contains the codes inactive and resolved that mark the AllergyIntolerance as no longer active.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceClinicalStatus"
        }],
        "strength" : "required",
        "description" : "The clinical status of the allergy or intolerance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-clinical"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.status"
      },
      {
        "identity" : "rim",
        "map" : "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"clinicalStatus\", moodCode=EVN].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.verificationStatus",
      "path" : "AllergyIntolerance.verificationStatus",
      "short" : "unconfirmed | confirmed | refuted | entered-in-error",
      "definition" : "Assertion about certainty associated with the propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical product).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.verificationStatus",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "condition" : ["ait-1",
      "ait-2"],
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the status contains the codes refuted and entered-in-error that mark the AllergyIntolerance as not currently valid.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceVerificationStatus"
        }],
        "strength" : "required",
        "description" : "Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-verification"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.status"
      },
      {
        "identity" : "rim",
        "map" : "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"verificationStatus\", moodCode=EVN].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.type",
      "path" : "AllergyIntolerance.type",
      "short" : "allergy | intolerance - Underlying mechanism (if known)",
      "definition" : "Identification of the underlying physiological mechanism for the reaction risk.",
      "comment" : "Allergic (typically immune-mediated) reactions have been traditionally regarded as an indicator for potential escalation to significant future risk. Contemporary knowledge suggests that some reactions previously thought to be immune-mediated are, in fact, non-immune, but in some cases can still pose a life threatening risk. It is acknowledged that many clinicians might not be in a position to distinguish the mechanism of a particular reaction. Often the term \"allergy\" is used rather generically and may overlap with the use of \"intolerance\" - in practice the boundaries between these two concepts might not be well-defined or understood. This data element is included nevertheless, because many legacy systems have captured this attribute. Immunologic testing may provide supporting evidence for the basis of the reaction and the causative substance, but no tests are 100% sensitive or specific for sensitivity to a particular substance. If, as is commonly the case, it is unclear whether the reaction is due to an allergy or an intolerance, then the type element should be omitted from the resource.",
      "alias" : ["Category",
      "Class"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceType"
        }],
        "strength" : "required",
        "description" : "Identification of the underlying physiological mechanism for a Reaction Risk.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-type"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "IAM-9"
      },
      {
        "identity" : "rim",
        "map" : "code"
      }]
    },
    {
      "id" : "AllergyIntolerance.category",
      "path" : "AllergyIntolerance.category",
      "short" : "food | medication | environment | biologic",
      "definition" : "Category of the identified substance.",
      "comment" : "This data element has been included because it is currently being captured in some clinical systems. This data can be derived from the substance where coding systems are used, and is effectively redundant in that situation.  When searching on category, consider the implications of AllergyIntolerance resources without a category.  For example, when searching on category = medication, medication allergies that don't have a category valued will not be returned.  Refer to [search](search.html) for more information on how to search category with a :missing modifier to get allergies that don't have a category.  Additionally, category should be used with caution because category can be subjective based on the sender.",
      "alias" : ["Category",
      "Type",
      "Reaction Type",
      "Class"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.category",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCategory"
        }],
        "strength" : "required",
        "description" : "Category of an identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-category"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "AL1-2"
      },
      {
        "identity" : "rim",
        "map" : "value < IntoleranceValue (Agent)"
      }]
    },
    {
      "id" : "AllergyIntolerance.criticality",
      "path" : "AllergyIntolerance.criticality",
      "short" : "low | high | unable-to-assess",
      "definition" : "Estimate of the potential clinical harm, or seriousness, of the reaction to the identified substance.",
      "comment" : "The default criticality value for any propensity to an adverse reaction should be 'Low Risk', indicating at the very least a relative contraindication to deliberate or voluntary exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity for a more serious or potentially life-threatening reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate or voluntary exposure to the substance. If this element is missing, the criticality is unknown (though it may be known elsewhere).  Systems that capture a severity at the condition level are actually representing the concept of criticality whereas the severity documented at the reaction level is representing the true reaction severity.  Existing systems that are capturing both condition criticality and reaction severity may use the term \"severity\" to represent both.  Criticality is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-dependent.",
      "alias" : ["Severity",
      "Seriousness",
      "Contra-indication",
      "Risk"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.criticality",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCriticality"
        }],
        "strength" : "required",
        "description" : "Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.grade"
      },
      {
        "identity" : "v2",
        "map" : "AL1-4"
      },
      {
        "identity" : "rim",
        "map" : "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.code",
      "path" : "AllergyIntolerance.code",
      "short" : "Code that identifies the allergy or intolerance",
      "definition" : "Code for an allergy or intolerance statement (either a positive or a negated/excluded statement).  This may be a code for a substance or pharmaceutical product that is considered to be responsible for the adverse reaction risk (e.g., \"Latex\"), an allergy or intolerance condition (e.g., \"Latex allergy\"), or a negated/excluded code for a specific substance or class (e.g., \"No latex allergy\") or a general or categorical negated statement (e.g.,  \"No known allergy\", \"No known drug allergies\").  Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.",
      "comment" : "It is strongly recommended that this element be populated using a terminology, where possible. For example, some terminologies used include RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10, UNII, and ATC. Plain text should only be used if there is no appropriate terminology available. Additional details can be specified in the text.\r\rWhen a substance or product code is specified for the 'code' element, the \"default\" semantic context is that this is a positive statement of an allergy or intolerance (depending on the value of the 'type' element, if present) condition to the specified substance/product.  In the corresponding SNOMED CT allergy model, the specified substance/product is the target (destination) of the \"Causative agent\" relationship.\r\rThe 'substanceExposureRisk' extension is available as a structured and more flexible alternative to the 'code' element for making positive or negative allergy or intolerance statements.  This extension provides the capability to make \"no known allergy\" (or \"no risk of adverse reaction\") statements regarding any coded substance/product (including cases when a pre-coordinated \"no allergy to x\" concept for that substance/product does not exist).  If the 'substanceExposureRisk' extension is present, the AllergyIntolerance.code element SHALL be omitted.",
      "alias" : ["Code"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.code",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCode"
        }],
        "strength" : "example",
        "description" : "Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-code"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.what[x]"
      },
      {
        "identity" : "v2",
        "map" : "AL1-3 / IAM-3"
      },
      {
        "identity" : "rim",
        "map" : "substance/product:\r\r.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rnegated/excluded substance/product:\r\r.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rpositive or negated/excluded condition/situation:\r\rObservation.code=ASSERTION; Observation.value"
      }]
    },
    {
      "id" : "AllergyIntolerance.patient",
      "path" : "AllergyIntolerance.patient",
      "short" : "Who the sensitivity is for",
      "definition" : "The patient who has the allergy or intolerance.",
      "alias" : ["Patient"],
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.patient",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Patient"]
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.subject[x]"
      },
      {
        "identity" : "v2",
        "map" : "(PID-3)"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=SBJ].role[classCode=PAT]"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.subject"
      }]
    },
    {
      "id" : "AllergyIntolerance.encounter",
      "path" : "AllergyIntolerance.encounter",
      "short" : "Encounter when the allergy or intolerance was asserted",
      "definition" : "The encounter when the allergy or intolerance was asserted.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.encounter",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Encounter"]
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.context"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]"
      }]
    },
    {
      "id" : "AllergyIntolerance.onset[x]",
      "path" : "AllergyIntolerance.onset[x]",
      "short" : "When allergy or intolerance was identified",
      "definition" : "Estimated or actual date,  date-time, or age when allergy or intolerance was identified.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.onset[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "dateTime"
      },
      {
        "code" : "Age"
      },
      {
        "code" : "Period"
      },
      {
        "code" : "Range"
      },
      {
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.init"
      },
      {
        "identity" : "rim",
        "map" : "effectiveTime.low"
      }]
    },
    {
      "id" : "AllergyIntolerance.recordedDate",
      "path" : "AllergyIntolerance.recordedDate",
      "short" : "Date first version of the resource instance was recorded",
      "definition" : "The recordedDate represents when this particular AllergyIntolerance record was created in the system, which is often a system-generated date.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.recordedDate",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "dateTime"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.recorded"
      },
      {
        "identity" : "v2",
        "map" : "IAM-13"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=AUT].time"
      }]
    },
    {
      "id" : "AllergyIntolerance.recorder",
      "path" : "AllergyIntolerance.recorder",
      "short" : "Who recorded the sensitivity",
      "definition" : "Individual who recorded the record and takes responsibility for its content.",
      "alias" : ["Author"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.recorder",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Practitioner",
        "http://hl7.org/fhir/StructureDefinition/Patient",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson"]
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.author"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=AUT].role"
      }]
    },
    {
      "id" : "AllergyIntolerance.asserter",
      "path" : "AllergyIntolerance.asserter",
      "short" : "Source of the information about the allergy",
      "definition" : "The source of the information about the allergy that is recorded.",
      "comment" : "The recorder takes responsibility for the content, but can reference the source from where they got it.",
      "alias" : ["Source",
      "Informant"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.asserter",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Patient",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson",
        "http://hl7.org/fhir/StructureDefinition/Practitioner"]
      }],
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.source"
      },
      {
        "identity" : "v2",
        "map" : "IAM-14 (if patient) / IAM-18 (if practitioner)"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=INF].role"
      }]
    },
    {
      "id" : "AllergyIntolerance.lastOccurrence",
      "path" : "AllergyIntolerance.lastOccurrence",
      "short" : "Date(/time) of last known occurrence of a reaction",
      "definition" : "Represents the date and/or time of the last known occurrence of a reaction event.",
      "comment" : "This date may be replicated by one of the Onset of Reaction dates. Where a textual representation of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment element should be used.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.lastOccurrence",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "dateTime"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)].effectiveTime"
      }]
    },
    {
      "id" : "AllergyIntolerance.note",
      "path" : "AllergyIntolerance.note",
      "short" : "Additional text not captured in other fields",
      "definition" : "Additional narrative about the propensity for the Adverse Reaction, not captured in other fields.",
      "comment" : "For example: including reason for flagging a seriousness of 'High Risk'; and instructions related to future exposure or administration of the substance, such as administration within an Intensive Care Unit or under corticosteroid cover. The notes should be related to an allergy or intolerance as a condition in general and not related to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description and  AllergyIntolerance.event.notes.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.note",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Annotation"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "subjectOf.observationEvent[code=\"annotation\"].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction",
      "path" : "AllergyIntolerance.reaction",
      "short" : "Adverse Reaction Events linked to exposure to substance",
      "definition" : "Details about each adverse reaction event linked to exposure to the identified substance.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.reaction",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "Element"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.id",
      "path" : "AllergyIntolerance.reaction.id",
      "representation" : ["xmlAttr"],
      "short" : "xml:id (or equivalent in JSON)",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.extension",
      "path" : "AllergyIntolerance.reaction.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.modifierExtension",
      "path" : "AllergyIntolerance.reaction.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.substance",
      "path" : "AllergyIntolerance.reaction.substance",
      "short" : "Specific substance or pharmaceutical product considered to be responsible for event",
      "definition" : "Identification of the specific substance (or pharmaceutical product) considered to be responsible for the Adverse Reaction event. Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.",
      "comment" : "Coding of the specific substance (or pharmaceutical product) with a terminology capable of triggering decision support should be used wherever possible.  The 'code' element allows for the use of a specific substance or pharmaceutical product, or a group or class of substances. In the case of an allergy or intolerance to a class of substances, (for example, \"penicillins\"), the 'reaction.substance' element could be used to code the specific substance that was identified as having caused the reaction (for example, \"amoxycillin\"). Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable when a specific substance has been recorded in 'code'.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.reaction.substance",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "SubstanceCode"
        }],
        "strength" : "example",
        "description" : "Codes defining the type of the substance (including pharmaceutical products).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/substance-code"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].participation[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.manifestation",
      "path" : "AllergyIntolerance.reaction.manifestation",
      "short" : "Clinical symptoms/signs associated with the Event",
      "definition" : "Clinical symptoms and/or signs that are observed or associated with the adverse reaction event.",
      "comment" : "Manifestation can be expressed as a single word, phrase or brief description. For example: nausea, rash or no reaction. It is preferable that manifestation should be coded with a terminology, where possible. The values entered here may be used to display on an application screen as part of a list of adverse reactions, as recommended in the UK NHS CUI guidelines.  Terminologies commonly used include, but are not limited to, SNOMED CT or ICD10.",
      "alias" : ["Symptoms",
      "Signs"],
      "min" : 1,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.reaction.manifestation",
        "min" : 1,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "Manifestation"
        }],
        "strength" : "example",
        "description" : "Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/clinical-findings"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "AL1-5"
      },
      {
        "identity" : "rim",
        "map" : "code"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.description",
      "path" : "AllergyIntolerance.reaction.description",
      "short" : "Description of the event as a whole",
      "definition" : "Text description about the reaction as a whole, including details of the manifestation if required.",
      "comment" : "Use the description to provide any details of a particular event of the occurred reaction such as circumstances, reaction specifics, what happened before/after. Information, related to the event, but not describing a particular care should be captured in the comment field. For example: at the age of four, the patient was given penicillin for strep throat and subsequently developed severe hives.",
      "alias" : ["Narrative",
      "Text"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.reaction.description",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "text"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.onset",
      "path" : "AllergyIntolerance.reaction.onset",
      "short" : "Date(/time) when manifestations showed",
      "definition" : "Record of the date and/or time of the onset of the Reaction.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.reaction.onset",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "dateTime"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "v2",
        "map" : "AL1-6"
      },
      {
        "identity" : "rim",
        "map" : "effectiveTime.low"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.severity",
      "path" : "AllergyIntolerance.reaction.severity",
      "short" : "mild | moderate | severe (of event as a whole)",
      "definition" : "Clinical assessment of the severity of the reaction event as a whole, potentially considering multiple different manifestations.",
      "comment" : "It is acknowledged that this assessment is very subjective. There may be some specific practice domains where objective scales have been applied. Objective scales can be included in this model as extensions.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.reaction.severity",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceSeverity"
        }],
        "strength" : "required",
        "description" : "Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/reaction-event-severity"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.exposureRoute",
      "path" : "AllergyIntolerance.reaction.exposureRoute",
      "short" : "How the subject was exposed to the substance",
      "definition" : "Identification of the route by which the subject was exposed to the substance.",
      "comment" : "Coding of the route of exposure with a terminology should be used wherever possible.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "AllergyIntolerance.reaction.exposureRoute",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "RouteOfAdministration"
        }],
        "strength" : "example",
        "description" : "A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/route-codes"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].routeCode"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.note",
      "path" : "AllergyIntolerance.reaction.note",
      "short" : "Text about event not captured in other fields",
      "definition" : "Additional text about the adverse reaction event not captured in other fields.",
      "comment" : "Use this field to record information indirectly related to a particular event and not captured in the description. For example: Clinical records are no longer available, recorded based on information provided to the patient by her mother and her mother is deceased.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "AllergyIntolerance.reaction.note",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Annotation"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "subjectOf.observationEvent[code=\"annotation\"].value"
      }]
    }]
  },
  "differential" : {
    "element" : [{
      "id" : "AllergyIntolerance",
      "path" : "AllergyIntolerance",
      "short" : "Allergy or Intolerance (generally: Risk of adverse reaction to a substance)",
      "definition" : "Risk of harmful or undesirable, physiological response which is unique to an individual and associated with exposure to a substance.",
      "comment" : "Substances include, but are not limited to: a therapeutic substance administered correctly at an appropriate dosage for the individual; food; material derived from plants or animals; or venom from insect stings.",
      "alias" : ["Allergy",
      "Intolerance",
      "Adverse Reaction"],
      "min" : 0,
      "max" : "*",
      "constraint" : [{
        "key" : "ait-1",
        "severity" : "error",
        "human" : "AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not entered-in-error.",
        "expression" : "verificationStatus='entered-in-error' or clinicalStatus.exists()",
        "xpath" : "f:verificationStatus/@value='entered-in-error' or exists(f:clinicalStatus)"
      },
      {
        "key" : "ait-2",
        "severity" : "error",
        "human" : "AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status is entered-in-error",
        "expression" : "verificationStatus!='entered-in-error' or clinicalStatus.empty()",
        "xpath" : "f:verificationStatus/@value!='entered-in-error' or not(exists(f:clinicalStatus))"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "Observation[classCode=OBS, moodCode=EVN]"
      }]
    },
    {
      "id" : "AllergyIntolerance.identifier",
      "path" : "AllergyIntolerance.identifier",
      "short" : "External ids for this item",
      "definition" : "Business identifiers assigned to this AllergyIntolerance by the performer or other systems which remain constant as the resource is updated and propagates from server to server.",
      "comment" : "This is a business identifier, not a resource identifier (see [discussion](resource.html#identifiers)).  It is best practice for the identifier to only appear on a single resource instance, however business practices may occasionally dictate that multiple resource instances with the same identifier can exist - possibly even with different resource types.  For example, multiple Patient and a Person resource instance might share the same social insurance number.",
      "requirements" : "Allows identification of the AllergyIntolerance as it is known by various participating systems and in a way that remains consistent across servers.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Identifier"
      }],
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.identifier"
      },
      {
        "identity" : "v2",
        "map" : "IAM-7"
      },
      {
        "identity" : "rim",
        "map" : "id"
      }]
    },
    {
      "id" : "AllergyIntolerance.clinicalStatus",
      "path" : "AllergyIntolerance.clinicalStatus",
      "short" : "active | inactive | resolved",
      "definition" : "The clinical status of the allergy or intolerance.",
      "comment" : "Refer to [discussion](extensibility.html#Special-Case) if clincalStatus is missing data.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "condition" : ["ait-1",
      "ait-2"],
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the status contains the codes inactive and resolved that mark the AllergyIntolerance as no longer active.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceClinicalStatus"
        }],
        "strength" : "required",
        "description" : "The clinical status of the allergy or intolerance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-clinical"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.status"
      },
      {
        "identity" : "rim",
        "map" : "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"clinicalStatus\", moodCode=EVN].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.verificationStatus",
      "path" : "AllergyIntolerance.verificationStatus",
      "short" : "unconfirmed | confirmed | refuted | entered-in-error",
      "definition" : "Assertion about certainty associated with the propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical product).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "condition" : ["ait-1",
      "ait-2"],
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the status contains the codes refuted and entered-in-error that mark the AllergyIntolerance as not currently valid.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceVerificationStatus"
        }],
        "strength" : "required",
        "description" : "Assertion about certainty associated with a propensity, or potential risk, of a reaction to the identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-verification"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.status"
      },
      {
        "identity" : "rim",
        "map" : "Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=\"verificationStatus\", moodCode=EVN].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.type",
      "path" : "AllergyIntolerance.type",
      "short" : "allergy | intolerance - Underlying mechanism (if known)",
      "definition" : "Identification of the underlying physiological mechanism for the reaction risk.",
      "comment" : "Allergic (typically immune-mediated) reactions have been traditionally regarded as an indicator for potential escalation to significant future risk. Contemporary knowledge suggests that some reactions previously thought to be immune-mediated are, in fact, non-immune, but in some cases can still pose a life threatening risk. It is acknowledged that many clinicians might not be in a position to distinguish the mechanism of a particular reaction. Often the term \"allergy\" is used rather generically and may overlap with the use of \"intolerance\" - in practice the boundaries between these two concepts might not be well-defined or understood. This data element is included nevertheless, because many legacy systems have captured this attribute. Immunologic testing may provide supporting evidence for the basis of the reaction and the causative substance, but no tests are 100% sensitive or specific for sensitivity to a particular substance. If, as is commonly the case, it is unclear whether the reaction is due to an allergy or an intolerance, then the type element should be omitted from the resource.",
      "alias" : ["Category",
      "Class"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceType"
        }],
        "strength" : "required",
        "description" : "Identification of the underlying physiological mechanism for a Reaction Risk.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-type"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "IAM-9"
      },
      {
        "identity" : "rim",
        "map" : "code"
      }]
    },
    {
      "id" : "AllergyIntolerance.category",
      "path" : "AllergyIntolerance.category",
      "short" : "food | medication | environment | biologic",
      "definition" : "Category of the identified substance.",
      "comment" : "This data element has been included because it is currently being captured in some clinical systems. This data can be derived from the substance where coding systems are used, and is effectively redundant in that situation.  When searching on category, consider the implications of AllergyIntolerance resources without a category.  For example, when searching on category = medication, medication allergies that don't have a category valued will not be returned.  Refer to [search](search.html) for more information on how to search category with a :missing modifier to get allergies that don't have a category.  Additionally, category should be used with caution because category can be subjective based on the sender.",
      "alias" : ["Category",
      "Type",
      "Reaction Type",
      "Class"],
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "code"
      }],
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCategory"
        }],
        "strength" : "required",
        "description" : "Category of an identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-category"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "AL1-2"
      },
      {
        "identity" : "rim",
        "map" : "value < IntoleranceValue (Agent)"
      }]
    },
    {
      "id" : "AllergyIntolerance.criticality",
      "path" : "AllergyIntolerance.criticality",
      "short" : "low | high | unable-to-assess",
      "definition" : "Estimate of the potential clinical harm, or seriousness, of the reaction to the identified substance.",
      "comment" : "The default criticality value for any propensity to an adverse reaction should be 'Low Risk', indicating at the very least a relative contraindication to deliberate or voluntary exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity for a more serious or potentially life-threatening reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate or voluntary exposure to the substance. If this element is missing, the criticality is unknown (though it may be known elsewhere).  Systems that capture a severity at the condition level are actually representing the concept of criticality whereas the severity documented at the reaction level is representing the true reaction severity.  Existing systems that are capturing both condition criticality and reaction severity may use the term \"severity\" to represent both.  Criticality is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-dependent.",
      "alias" : ["Severity",
      "Seriousness",
      "Contra-indication",
      "Risk"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCriticality"
        }],
        "strength" : "required",
        "description" : "Estimate of the potential clinical harm, or seriousness, of a reaction to an identified substance.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.grade"
      },
      {
        "identity" : "v2",
        "map" : "AL1-4"
      },
      {
        "identity" : "rim",
        "map" : "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.code",
      "path" : "AllergyIntolerance.code",
      "short" : "Code that identifies the allergy or intolerance",
      "definition" : "Code for an allergy or intolerance statement (either a positive or a negated/excluded statement).  This may be a code for a substance or pharmaceutical product that is considered to be responsible for the adverse reaction risk (e.g., \"Latex\"), an allergy or intolerance condition (e.g., \"Latex allergy\"), or a negated/excluded code for a specific substance or class (e.g., \"No latex allergy\") or a general or categorical negated statement (e.g.,  \"No known allergy\", \"No known drug allergies\").  Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.",
      "comment" : "It is strongly recommended that this element be populated using a terminology, where possible. For example, some terminologies used include RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10, UNII, and ATC. Plain text should only be used if there is no appropriate terminology available. Additional details can be specified in the text.\r\rWhen a substance or product code is specified for the 'code' element, the \"default\" semantic context is that this is a positive statement of an allergy or intolerance (depending on the value of the 'type' element, if present) condition to the specified substance/product.  In the corresponding SNOMED CT allergy model, the specified substance/product is the target (destination) of the \"Causative agent\" relationship.\r\rThe 'substanceExposureRisk' extension is available as a structured and more flexible alternative to the 'code' element for making positive or negative allergy or intolerance statements.  This extension provides the capability to make \"no known allergy\" (or \"no risk of adverse reaction\") statements regarding any coded substance/product (including cases when a pre-coordinated \"no allergy to x\" concept for that substance/product does not exist).  If the 'substanceExposureRisk' extension is present, the AllergyIntolerance.code element SHALL be omitted.",
      "alias" : ["Code"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceCode"
        }],
        "strength" : "example",
        "description" : "Type of the substance/product, allergy or intolerance condition, or negation/exclusion codes for reporting no known allergies.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/allergyintolerance-code"
      },
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.what[x]"
      },
      {
        "identity" : "v2",
        "map" : "AL1-3 / IAM-3"
      },
      {
        "identity" : "rim",
        "map" : "substance/product:\r\r.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rnegated/excluded substance/product:\r\r.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]\r\rpositive or negated/excluded condition/situation:\r\rObservation.code=ASSERTION; Observation.value"
      }]
    },
    {
      "id" : "AllergyIntolerance.patient",
      "path" : "AllergyIntolerance.patient",
      "short" : "Who the sensitivity is for",
      "definition" : "The patient who has the allergy or intolerance.",
      "alias" : ["Patient"],
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Patient"]
      }],
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.subject[x]"
      },
      {
        "identity" : "v2",
        "map" : "(PID-3)"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=SBJ].role[classCode=PAT]"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.subject"
      }]
    },
    {
      "id" : "AllergyIntolerance.encounter",
      "path" : "AllergyIntolerance.encounter",
      "short" : "Encounter when the allergy or intolerance was asserted",
      "definition" : "The encounter when the allergy or intolerance was asserted.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Encounter"]
      }],
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.context"
      },
      {
        "identity" : "rim",
        "map" : ".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]"
      }]
    },
    {
      "id" : "AllergyIntolerance.onset[x]",
      "path" : "AllergyIntolerance.onset[x]",
      "short" : "When allergy or intolerance was identified",
      "definition" : "Estimated or actual date,  date-time, or age when allergy or intolerance was identified.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      },
      {
        "code" : "Age"
      },
      {
        "code" : "Period"
      },
      {
        "code" : "Range"
      },
      {
        "code" : "string"
      }],
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.init"
      },
      {
        "identity" : "rim",
        "map" : "effectiveTime.low"
      }]
    },
    {
      "id" : "AllergyIntolerance.recordedDate",
      "path" : "AllergyIntolerance.recordedDate",
      "short" : "Date first version of the resource instance was recorded",
      "definition" : "The recordedDate represents when this particular AllergyIntolerance record was created in the system, which is often a system-generated date.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      }],
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.recorded"
      },
      {
        "identity" : "v2",
        "map" : "IAM-13"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=AUT].time"
      }]
    },
    {
      "id" : "AllergyIntolerance.recorder",
      "path" : "AllergyIntolerance.recorder",
      "short" : "Who recorded the sensitivity",
      "definition" : "Individual who recorded the record and takes responsibility for its content.",
      "alias" : ["Author"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Practitioner",
        "http://hl7.org/fhir/StructureDefinition/Patient",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson"]
      }],
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.author"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=AUT].role"
      }]
    },
    {
      "id" : "AllergyIntolerance.asserter",
      "path" : "AllergyIntolerance.asserter",
      "short" : "Source of the information about the allergy",
      "definition" : "The source of the information about the allergy that is recorded.",
      "comment" : "The recorder takes responsibility for the content, but can reference the source from where they got it.",
      "alias" : ["Source",
      "Informant"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Patient",
        "http://hl7.org/fhir/StructureDefinition/RelatedPerson",
        "http://hl7.org/fhir/StructureDefinition/Practitioner"]
      }],
      "isSummary" : true,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.source"
      },
      {
        "identity" : "v2",
        "map" : "IAM-14 (if patient) / IAM-18 (if practitioner)"
      },
      {
        "identity" : "rim",
        "map" : ".participation[typeCode=INF].role"
      }]
    },
    {
      "id" : "AllergyIntolerance.lastOccurrence",
      "path" : "AllergyIntolerance.lastOccurrence",
      "short" : "Date(/time) of last known occurrence of a reaction",
      "definition" : "Represents the date and/or time of the last known occurrence of a reaction event.",
      "comment" : "This date may be replicated by one of the Onset of Reaction dates. Where a textual representation of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment element should be used.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)].effectiveTime"
      }]
    },
    {
      "id" : "AllergyIntolerance.note",
      "path" : "AllergyIntolerance.note",
      "short" : "Additional text not captured in other fields",
      "definition" : "Additional narrative about the propensity for the Adverse Reaction, not captured in other fields.",
      "comment" : "For example: including reason for flagging a seriousness of 'High Risk'; and instructions related to future exposure or administration of the substance, such as administration within an Intensive Care Unit or under corticosteroid cover. The notes should be related to an allergy or intolerance as a condition in general and not related to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description and  AllergyIntolerance.event.notes.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Annotation"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "subjectOf.observationEvent[code=\"annotation\"].value"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction",
      "path" : "AllergyIntolerance.reaction",
      "short" : "Adverse Reaction Events linked to exposure to substance",
      "definition" : "Details about each adverse reaction event linked to exposure to the identified substance.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code <= CommonClinicalObservationType, value <= ObservationValue (Reaction Type)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.substance",
      "path" : "AllergyIntolerance.reaction.substance",
      "short" : "Specific substance or pharmaceutical product considered to be responsible for event",
      "definition" : "Identification of the specific substance (or pharmaceutical product) considered to be responsible for the Adverse Reaction event. Note: the substance for a specific reaction may be different from the substance identified as the cause of the risk, but it must be consistent with it. For instance, it may be a more specific substance (e.g. a brand medication) or a composite product that includes the identified substance. It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reaction.substance.",
      "comment" : "Coding of the specific substance (or pharmaceutical product) with a terminology capable of triggering decision support should be used wherever possible.  The 'code' element allows for the use of a specific substance or pharmaceutical product, or a group or class of substances. In the case of an allergy or intolerance to a class of substances, (for example, \"penicillins\"), the 'reaction.substance' element could be used to code the specific substance that was identified as having caused the reaction (for example, \"amoxycillin\"). Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable when a specific substance has been recorded in 'code'.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "SubstanceCode"
        }],
        "strength" : "example",
        "description" : "Codes defining the type of the substance (including pharmaceutical products).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/substance-code"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].participation[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code <= ExposureAgentEntityType]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.manifestation",
      "path" : "AllergyIntolerance.reaction.manifestation",
      "short" : "Clinical symptoms/signs associated with the Event",
      "definition" : "Clinical symptoms and/or signs that are observed or associated with the adverse reaction event.",
      "comment" : "Manifestation can be expressed as a single word, phrase or brief description. For example: nausea, rash or no reaction. It is preferable that manifestation should be coded with a terminology, where possible. The values entered here may be used to display on an application screen as part of a list of adverse reactions, as recommended in the UK NHS CUI guidelines.  Terminologies commonly used include, but are not limited to, SNOMED CT or ICD10.",
      "alias" : ["Symptoms",
      "Signs"],
      "min" : 1,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "Manifestation"
        }],
        "strength" : "example",
        "description" : "Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction Event.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/clinical-findings"
      },
      "mapping" : [{
        "identity" : "v2",
        "map" : "AL1-5"
      },
      {
        "identity" : "rim",
        "map" : "code"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.description",
      "path" : "AllergyIntolerance.reaction.description",
      "short" : "Description of the event as a whole",
      "definition" : "Text description about the reaction as a whole, including details of the manifestation if required.",
      "comment" : "Use the description to provide any details of a particular event of the occurred reaction such as circumstances, reaction specifics, what happened before/after. Information, related to the event, but not describing a particular care should be captured in the comment field. For example: at the age of four, the patient was given penicillin for strep throat and subsequently developed severe hives.",
      "alias" : ["Narrative",
      "Text"],
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "string"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "text"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.onset",
      "path" : "AllergyIntolerance.reaction.onset",
      "short" : "Date(/time) when manifestations showed",
      "definition" : "Record of the date and/or time of the onset of the Reaction.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "dateTime"
      }],
      "mapping" : [{
        "identity" : "v2",
        "map" : "AL1-6"
      },
      {
        "identity" : "rim",
        "map" : "effectiveTime.low"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.severity",
      "path" : "AllergyIntolerance.reaction.severity",
      "short" : "mild | moderate | severe (of event as a whole)",
      "definition" : "Clinical assessment of the severity of the reaction event as a whole, potentially considering multiple different manifestations.",
      "comment" : "It is acknowledged that this assessment is very subjective. There may be some specific practice domains where objective scales have been applied. Objective scales can be included in this model as extensions.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "AllergyIntoleranceSeverity"
        }],
        "strength" : "required",
        "description" : "Clinical assessment of the severity of a reaction event as a whole, potentially considering multiple different manifestations.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/reaction-event-severity"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value <= SeverityObservation (Severity Level)]"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.exposureRoute",
      "path" : "AllergyIntolerance.reaction.exposureRoute",
      "short" : "How the subject was exposed to the substance",
      "definition" : "Identification of the route by which the subject was exposed to the substance.",
      "comment" : "Coding of the route of exposure with a terminology should be used wherever possible.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "RouteOfAdministration"
        }],
        "strength" : "example",
        "description" : "A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/route-codes"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code <= ExposureCode].routeCode"
      }]
    },
    {
      "id" : "AllergyIntolerance.reaction.note",
      "path" : "AllergyIntolerance.reaction.note",
      "short" : "Text about event not captured in other fields",
      "definition" : "Additional text about the adverse reaction event not captured in other fields.",
      "comment" : "Use this field to record information indirectly related to a particular event and not captured in the description. For example: Clinical records are no longer available, recorded based on information provided to the patient by her mother and her mother is deceased.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Annotation"
      }],
      "mapping" : [{
        "identity" : "rim",
        "map" : "subjectOf.observationEvent[code=\"annotation\"].value"
      }]
    }]
  }
}

Примечание к использованию: мы очень стараемся приводить корректные и полезные примеры, но нормативно они не являются частью спецификации.